Document Detail


Clarithromycin induced reversible sensorineural hearing loss.
MedLine Citation:
PMID:  21838098     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: We present a rare case of reversible sensorineural hearing loss caused by clarithromycin.
METHODS: We present a case report of hearing loss following clarithromycin administration; we also review the current literature and case reports concerning macrolides and, in particular, clarithromycin induced hearing loss.
RESULTS: A young pregnant woman presented with sensorineural hearing loss after clarithromycin intake. The subject's hearing returned to normal limits after drug discontinuation and short-term treatment with low dose steroids.
CONCLUSION: Newer macrolides are considered to be safer regarding ototoxic effects, and a few cases have been previously described. The present case adds to the body of knowledge concerning clarithromycin ototoxicity. Clinicians should be aware of this rare complication and a thorough otologic history should be established prior to macrolide administration. A baseline audiogram and close observation for patients at higher risk is suggested to identify patients with prior hearing loss and serve as baseline for future reference.
Authors:
J K Hajiioannou; V Florou; P Kousoulis; M Fragkos; E Moshovakis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  B-ENT     Volume:  7     ISSN:  1781-782X     ISO Abbreviation:  B-ENT     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101247842     Medline TA:  B-ENT     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  127-30     Citation Subset:  IM    
Affiliation:
ENT Department of General Hospital of Nikea, Piraeus, Greece.
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