Document Detail

Citrus red mite (Panonychus citri) may be an important allergen in the development of asthma among exposed children.
MedLine Citation:
PMID:  11359426     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recent investigations have demonstrated that spider mites are important allergens in the development of asthma in fruit-cultivating farmers. OBJECTIVE: The aim of this study was to evaluate the sensitization rate to the citrus red mite (Panonychus citri) in children living in rural areas, and to determine the allergenic cross-reactivity with other mites. METHODS: A total of 7254 children (ages 7-15 years) living in rural areas were enrolled, and each subject was evaluated by a questionnaire and a skin prick test. Allergenic cross-reactivity was evaluated by ELISA inhibition tests. RESULTS: The most common sensitizing allergens were house dust mites, followed by citrus red mite and cockroach. High serum-specific IgE bindings to the citrus red mite were detected in 21 of 100 randomly selected subjects. The prevalence of asthma was higher among those with positive skin responses to the citrus red mite than with negative skin responses to this mite. ELISA inhibition tests showed that IgE bindings to this mite were minimally inhibited with additions of domestic mites. CONCLUSION: Spider mites such as the citrus red mite may be important outdoor allergens among children living in rural areas, and spider mite-derived allergens have unique allergenic determinants compared with domestic mites.
Y K Kim; H S Park; H Y Kim; Y K Jee; J W Son; J M Bae; M H Lee; S H Cho; K U Min; Y Y Kim
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology     Volume:  31     ISSN:  0954-7894     ISO Abbreviation:  Clin. Exp. Allergy     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-05-21     Completed Date:  2001-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8906443     Medline TA:  Clin Exp Allergy     Country:  England    
Other Details:
Languages:  eng     Pagination:  582-9     Citation Subset:  IM    
Department of Internal Medicine, Seoul National University College of Medicine, Korea.
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MeSH Terms
Allergens / adverse effects*
Asthma / chemically induced*,  epidemiology
Child Welfare
Citrus / adverse effects
Confidence Intervals
Cross Reactions / physiology
Environmental Exposure / adverse effects
Immunoglobulin E / blood
Respiratory Sounds / physiopathology
Rural Health
Skin / chemistry
Trombiculidae / immunology*
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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