| Citalopram treatment of children and adolescents with obsessive-compulsive disorder: a preliminary report. | |
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MedLine Citation:
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PMID: 12839522 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of the present study was to assess the efficacy and tolerability of citalopram in the acute treatment of children and adolescents with obsessive compulsive disorder (OCD) during an 8-week, open-label study. Fifteen patients (six female, nine male) with a mean age of 12.1 +/- 3.3 years (range: 6-17 years) were treated with citalopram (range of dose: 20-30 mg/day, mean dose: 24 +/- 5.5 mg/day). The children's version of the Yale-Brown Obsessive-Compulsive scale (CY-BOCS) was rated at the baseline, at the 4th week and at the 8th week of treatment. Fourteen patients had a decrease in total score of CY-BOCS from baseline to the 4th week of treatment (P < 0.01) and the 8th week of treatment (P < 0.01). Sedation (n = 1) and insomnia (n = 1) were reported in the first weeks of treatment. The primary data suggest the efficacy and tolerability of citalopram in young patients with OCD. |
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Authors:
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Nahit Motavallý Mukaddes; Osman Abali; Nimet Kaynak |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Psychiatry and clinical neurosciences Volume: 57 ISSN: 1323-1316 ISO Abbreviation: Psychiatry Clin. Neurosci. Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-07-03 Completed Date: 2003-09-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9513551 Medline TA: Psychiatry Clin Neurosci Country: Australia |
Other Details:
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Languages: eng Pagination: 405-8 Citation Subset: IM |
Affiliation:
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Department of Child and Adolescent Psychiatry, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. nmotavalli@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antidepressive Agents / administration & dosage, therapeutic use* Child Citalopram / administration & dosage, therapeutic use* Female Humans Male Obsessive-Compulsive Disorder / drug therapy*, psychology Psychiatric Status Rating Scales |
| Chemical | |
Reg. No./Substance:
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0/Antidepressive Agents; 59729-33-8/Citalopram |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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