Document Detail


Cisplatinum and docetaxel for ovarian cancer in pregnancy.
MedLine Citation:
PMID:  19242705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There is limited data on chemotherapy for advanced ovarian cancer during pregnancy. Most women received cisplatin-based chemotherapy. There are no published reports on the use of docetaxel for ovarian cancer in pregnancy.
CASE: A 32-year-old pregnant lady underwent laparatomy at 18-week gestation for ruptured ovarian cyst. The pregnancy was the result of in vitro fertilization with intracytoplasmic sperm injection. Left salpingo-oophorectomy and omental biopsy were done. A diagnosis of stage IIIC, poorly differentiated papillary serous adenocarcinoma of the ovary was made. She was given four cycles of cisplatinum and docetaxel followed by cesarean hysterectomy, right salpingo-oophorectomy, and cytoreductive surgery. The mother is well and has completed six cycle of chemotherapy.
CONCLUSION: This is the first report on the use of docetaxel during pregnancy for ovarian cancer.
Authors:
Abdulrahim A Rouzi; Nora N Sahly; Naif F Sahly; Mahmoud S Alahwal
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-02-26
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  280     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-09-25     Completed Date:  2010-01-28     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  823-5     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, King Abdulaziz University, PO Box 80215, Jeddah 21589, Saudi Arabia. aarouzi@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma, Papillary / blood,  drug therapy*
Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
CA-125 Antigen / blood
Cesarean Section
Cisplatin / administration & dosage
Fatal Outcome
Female
Humans
Infant, Newborn
Ovarian Neoplasms / blood,  drug therapy*
Pregnancy
Pregnancy Complications, Neoplastic / blood,  drug therapy*,  surgery
Taxoids / administration & dosage
Chemical
Reg. No./Substance:
0/CA-125 Antigen; 0/Taxoids; 15663-27-1/Cisplatin; 15H5577CQD/docetaxel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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