| Cisplatin as second-line chemotherapy in the treatment of advanced or recurrent leiomyosarcoma of the uterus. A phase II trial of the Gynecologic Oncology Group. | |
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MedLine Citation:
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PMID: 3953489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty patients with advanced or recurrent leiomyosarcoma of the uterus who failed prior chemotherapy were placed on study by the Gynecologic Oncology Group. One patient had insufficient data to permit analysis. Of the remaining 19, there was only one objective response to cisplatin 50 mg/m2 intravenously every 3 weeks. Although toxicity was tolerable, there is little evidence of drug activity in patients with leiomyosarcomas of the uterus when the drug is given as second-line chemotherapy in the dose and schedule tested. |
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Authors:
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J T Thigpen; J A Blessing; G D Wilbanks |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of clinical oncology Volume: 9 ISSN: 0277-3732 ISO Abbreviation: Am. J. Clin. Oncol. Publication Date: 1986 Feb |
Date Detail:
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Created Date: 1986-04-10 Completed Date: 1986-04-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8207754 Medline TA: Am J Clin Oncol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 18-20 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cisplatin / therapeutic use* Drug Evaluation Female Humans Leiomyosarcoma / drug therapy* Middle Aged Uterine Neoplasms / drug therapy* |
| Grant Support | |
ID/Acronym/Agency:
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CA-12482/CA/NCI NIH HHS; CA-12534/CA/NCI NIH HHS; CA-13633/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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15663-27-1/Cisplatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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