| Cisapride improves gallbladder kinetics in patients affected with myotonic muscular dystrophy. | |
| | |
MedLine Citation:
|
PMID: 8509236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Smooth muscle involvement is relatively common in myotonic muscular dystrophy (MMD). The effects of cisapride on gallbladder motor function in myotonic patients have been investigated in 10 alithiasic patients and in 10 healthy volunteers. Gallbladder volumes were measured by ultrasonography in fasting state and 15, 30, 45 and 60 min after milk intake. The patients were treated with cisapride for two months, after which they underwent a second ultrasonographic examination. Gallbladder emptying was slower and less effective in dystrophic patients than in healthy volunteers. Cisapride was found to improve gallbladder kinetics (efficacy of contraction and rate of emptying) in patients affected with myotonic muscular dystrophy. |
| | |
Authors:
|
S Marchi; A Polloni; M Bellini; E Orsitto; F Costa; M Spataro; B Rossi; G Siciliano; M C Masi; E Tumino |
Related Documents
:
|
11568916 - Comparative analysis of pcr-deletion detection and immunohistochemistry in brazilian du... 9204976 - Detection of 16 p deletions by fish in patients with inv(16) or t(16;16) and acute myel... 11547956 - Decrease of neurons in the medullary arcuate nucleus in myotonic dystrophy. 19966786 - Large, rare chromosomal deletions associated with severe early-onset obesity. 3262326 - The use and misuse of upper gastrointestinal endoscopy. 1072556 - Late results from mucosal denudation for urinary bladder papillomatosis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of clinical pharmacology research Volume: 13 ISSN: 0251-1649 ISO Abbreviation: Int J Clin Pharmacol Res Publication Date: 1993 |
Date Detail:
|
Created Date: 1993-07-12 Completed Date: 1993-07-12 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8110183 Medline TA: Int J Clin Pharmacol Res Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 53-8 Citation Subset: IM |
Affiliation:
|
Gastroenterology Unit-First Medical Clinic, Pisa University, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cisapride Female Gallbladder / drug effects, physiopathology*, ultrasonography Humans Kinetics Liver Function Tests Male Muscular Dystrophies / physiopathology*, ultrasonography Piperidines / adverse effects, pharmacology* Serotonin Antagonists / adverse effects, pharmacology* |
| Chemical | |
Reg. No./Substance:
|
0/Piperidines; 0/Serotonin Antagonists; 81098-60-4/Cisapride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Post-operative analgesia with tramadol: a controlled study compared with an analgesic combination.
Next Document: Salivary steroid changes and physical performance in highly trained cyclists.