| Cirrhotic liver enhancement on dual-phase helical CT: comparison with noncirrhotic livers in 146 patients. | |
| | |
MedLine Citation:
|
PMID: 10541087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of this study was to prospectively determine any differences in vascular and liver enhancement between patients with cirrhosis and patients without cirrhosis during both the arterial and portal venous phases on dual-phase helical CT. SUBJECTS AND METHODS: Fifty-eight patients with histologically proven cirrhosis (group 1) and 88 without cirrhosis (group 2 = normal findings on CT, group 3 = metastases, group 4 = other liver diseases) underwent dual-phase helical CT of the liver. Attenuation values of liver and vessels were measured on unenhanced scans and on scans obtained during the arterial and portal venous phases. The mean enhancement values per time interval (5 sec) were determined. Results were analyzed taking into account various intrinsic patient parameters. RESULTS: We found no statistically significant difference in terms of mean vascular enhancement and mean liver enhancement during the arterial imaging phase for each time interval among all the groups. The mean peak enhancement and mean liver enhancement during the portal venous phase were significantly lower in group 1 than in other groups. Time to peak enhancement was significantly delayed in group 1. CONCLUSION: In spite of the hepatic arterial buffer response, mean liver enhancement during the arterial phase was not significantly different in patients with cirrhosis compared with patients without cirrhosis. Although portal vein enhancement did not differ significantly, enhancement of cirrhotic liver was significantly lower during the portal venous phase and delayed, presumably because of decreased peripheral portal perfusion. The contrast injection protocol may be tailored to optimize conspicuity of hypovascular tumor. |
| | |
Authors:
|
O Vignaux; P Legmann; J Coste; C Hoeffel; A Bonnin |
Related Documents
:
|
19476787 - Utility of transjugular intrahepatic portosystemic shunts in liver-transplant recipients. 8985257 - Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in pat... 3411097 - Splanchnic and renal extraction of circulating hyaluronan in patients with alcoholic li... 8249977 - A syndrome of cirrhosis, achlorhydria, small intestinal bacterial overgrowth, and fat m... 11557647 - Predictors of radiographic joint damage in patients with early rheumatoid arthritis. 8134177 - Increased expression of human leukocyte antigen-dr on pulmonary macrophages in bronchop... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: AJR. American journal of roentgenology Volume: 173 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 1999 Nov |
Date Detail:
|
Created Date: 1999-11-09 Completed Date: 1999-11-09 Revised Date: 2008-02-15 |
Medline Journal Info:
|
Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1193-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Radiology, Université René Descartes, Hôpital Cochin, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Carcinoma, Hepatocellular / pathology, radiography* Diagnosis, Differential Female Hepatic Artery / pathology, radiography Humans Hypertension, Portal / pathology, radiography Liver / pathology, radiography Liver Cirrhosis / pathology, radiography* Liver Neoplasms / pathology, radiography* Male Middle Aged Portal Vein / pathology, radiography Prospective Studies Radiographic Image Enhancement* Sensitivity and Specificity Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Spectrum of imaging findings of the liver in end-stage cirrhosis: Part II, focal abnormalities.
Next Document: Percutaneous liver biopsy: a cost-benefit analysis comparing sonographic and CT guidance.