Document Detail

Cirrhosis mortality and per capita consumption of distilled spirits, United States, 1949-1994: trend analysis.
MedLine Citation:
PMID:  10532899     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe, evaluate, and suggest interpretations for an observed aggregate-level relation between trends in mortality from cirrhosis and per capita consumption of distilled spirits in the United States. DESIGN: Trend analysis using data on US cirrhosis mortality and per capita alcohol consumption. RESULTS: There is a consistent long-term trend relation between mortality from cirrhosis and per capita consumption of distilled spirits in the United States from 1949 to 1994. Two instances of comparatively sharp drops in the consumption of spirits in the 1940s generated mixed results in predicting changes in cirrhosis mortality. CONCLUSIONS: An aggregate-level relation between trends in long-term cirrhosis mortality and the consumption of spirits falls considerably short of establishing a direct causal link between the two for individuals. Moreover, two sharp drops in the consumption of spirits generated only mixed results with respect to the short-term trend in cirrhosis. Nevertheless, the observed relation between the consumption of spirits and cirrhosis mortality merits further investigation.
R Roizen; W C Kerr; K M Fillmore
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Western journal of medicine     Volume:  171     ISSN:  0093-0415     ISO Abbreviation:  West. J. Med.     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-20     Completed Date:  1999-10-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410504     Medline TA:  West J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  83-7     Citation Subset:  AIM; IM    
Department of Behavioral Sciences, University of California at San Francisco, CA 14143, USA.
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MeSH Terms
Alcohol Drinking / adverse effects,  trends*
Liver Cirrhosis / mortality*
Liver Cirrhosis, Alcoholic / mortality
Mortality / trends
Regression Analysis
United States / epidemiology
Grant Support
Comment In:
West J Med. 1999 Aug;171(2):88   [PMID:  10510654 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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