Document Detail


Cirrhosis mortality and per capita consumption of distilled spirits, United States, 1949-94: trend analysis.
MedLine Citation:
PMID:  10480821     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To describe, evaluate, and suggest interpretations for an observed aggregate level relation between trends in mortality from cirrhosis and per capita consumption of distilled spirits in the United States.
DESIGN: Trend analysis using data on US cirrhosis mortality and per capita alcohol consumption.
RESULTS: There is a consistent long term trend relation between mortality from cirrhosis and per capita consumption of distilled spirits in the United States from 1949 to 1994. Two instances of comparatively sharp drops in the consumption of spirits earlier in the 1940s generated mixed results in predicting changes in cirrhosis mortality.
CONCLUSIONS: An aggregate level relation between trends in long term cirrhosis mortality and the consumption of spirits falls considerably short of establishing a direct causal link between the two for individuals. Moreover, two sharp drops in the consumption of spirits generated only mixed results with respect to the short term trend in cirrhosis. Nevertheless, the observed relation between the consumption of spirits and cirrhosis mortality merits further investigation.
Authors:
R Roizen; W C Kerr; K M Fillmore
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  319     ISSN:  0959-8138     ISO Abbreviation:  BMJ     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-22     Completed Date:  1999-10-22     Revised Date:  2013-04-17    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  666-70     Citation Subset:  AIM; IM    
Affiliation:
University of California, San Francisco, Department of Social and Behavioral Sciences Box 0612, San Francisco, CA 94143-0612, USA. ron@roizen.com
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / epidemiology,  mortality*
Humans
Liver Cirrhosis, Alcoholic / mortality*
Regression Analysis
United States / epidemiology
Grant Support
ID/Acronym/Agency:
AA09623/AA/NIAAA NIH HHS; KO1 AA00073/AA/NIAAA NIH HHS; R01 AA07034/AA/NIAAA NIH HHS
Comments/Corrections

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