Document Detail


Circumferential skin creases, cleft palate, typical face, intellectual disability and growth delay: "Circumferential skin creases Kunze type"
MedLine Citation:
PMID:  21262397     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Congenital symmetrical circumferential skin creases are a rare feature, often described as the "Michelin Tire Baby" syndrome and in general having a good prognosis. In some patients however, the circumferential skin creases are associated with other congenital malformations. We describe 2 unrelated patients presenting with multiple circumferential skin creases, growth retardation, developmental delay, a typical facial appearance and cleft palate. In literature, 6 patients with an almost identical clinical phenotype have been described. This well recognizable syndrome should be distinguished from the "Michelin Tire Baby" syndrome and we therefore propose the term "circumferential skin creases Kunze type".
Authors:
Leen Wouters; Celia Maria Rodriguez Rodriguez; Elena Porta Dapena; Vincent Vander Poorten; Koen Devriendt; Hilde Van Esch
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-21
Journal Detail:
Title:  European journal of medical genetics     Volume:  -     ISSN:  1878-0849     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101247089     Medline TA:  Eur J Med Genet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Masson SAS.
Affiliation:
Department of Paediatrics, Herestraat 49, B-3000 Leuven, Belgium.
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