Document Detail

Circumferential mucosal dissection and esophageal perforation in a patient with eosinophilic esophagitis.
MedLine Citation:
PMID:  18205276     Owner:  NLM     Status:  MEDLINE    
A young man with a previous history of episodes of mild solid food dysphagia was admitted with a total dysphagia. The esophagogastroduodenoscopy (EGDS) showed an extensive disruption of mucosal layer with a cul-de-sac in the lower part of the esophagus. Soon after the procedure, the patient suffered from an acute chest pain and subsequent CT scan demonstrated an intramural circumferential dissection of thoracic esophagus, and a mediastinal emphysema. An emergency right thoracotomy was performed, followed by a total esophagectomy with esophagogastroplasty and jejunostomy. The histopathology confirmed that mucosal and submucosal layers were circumferentially detached from muscular wall and showed an eosinophilic infiltration of the whole organ with necrosis and erosions of mucosal, submucosal and muscular layers. The diagnosis was esophageal perforation in eosinophilic esophagitis.
Gennaro Liguori; Maurizio Cortale; Fabrizio Cimino; Michele Sozzi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  14     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-21     Completed Date:  2008-05-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  803-4     Citation Subset:  IM    
Department of General and Thoracic Surgery, Cattinara Hospital, Strada di Fiume 447, Trieste 34149, Italy.
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MeSH Terms
Endoscopy, Digestive System / adverse effects*
Eosinophilia / pathology*
Esophageal Perforation / etiology*,  pathology*,  surgery
Esophagitis / pathology*
Mucous Membrane / pathology

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