Document Detail


Circulatory shock associated with purulent peritonitis.
MedLine Citation:
PMID:  7258540     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relative roles of bacterial infection, fluid loss and myocardial failure were investigated in 24 patients in whom circulatory shock appeared as a complication of purulent peritonitis. The 13 acute survivors, including 6 hospital survivors, had strikingly lower initial plasma volumes and total blood volumes than the 11 patients who died. Differences in blood volume were not explained by differences in previous treatment or in duration of peritonitis. Acute survivors promptly improved after fluid repletion, whereas the patients who died failed to respond to the infusion of equivalent volumes of fluid. In contrast to acute survivors, the fatal cases demonstrated disproportionate increases in both right- and left-sided filling pressure, increases in pulmonary vascular resistance and decreased right and left ventricular work capability. These observations in patients complement experimental studies in which biventricular cardiac failure was implicated in the fatal progression of septic shock.
Authors:
J L Vincent; M H Weil; V Puri; R W Carlson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of surgery     Volume:  142     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1981 Aug 
Date Detail:
Created Date:  1981-09-25     Completed Date:  1981-09-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  262-70     Citation Subset:  AIM; IM; S    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Blood Volume
Female
Fluid Therapy / methods*
Hemodynamics
Humans
Male
Middle Aged
Peritonitis / complications*
Plasma Volume
Shock, Septic / etiology,  physiopathology,  therapy*
Grant Support
ID/Acronym/Agency:
GM 16462/GM/NIGMS NIH HHS; R01 HL 23015/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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