Document Detail


Circulatory responses to laryngeal mask airway insertion or tracheal intubation in normotensive and hypertensive patients.
MedLine Citation:
PMID:  7534216     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of laryngeal mask airway (LMA) insertion and tracheal intubation on circulatory responses were studied in normotensive (n = 24) and hypertensive (n = 22) patients. In a randomized, double-blind manner, LMA insertion or tracheal intubation was performed after induction of anaesthesia with thiopentone and muscle relaxation with succinylcholine. In both normotensive and hypertensive patients, heart rate (HR), mean arterial pressure (MAP) and rate-pressure product increased after tracheal intubation or LMA insertion compared with baseline (P < 0.05). The haemodynamic changes were greater after intubation than after LMA insertion (P < 0.05). Following intubation of the trachea or insertion of the LMA, HR increased more markedly in hypertensive patients than in normotensive patients (P < 0.05). Plasma adrenaline and noradrenaline concentrations after tracheal intubation or LMA insertion increased compared with baseline values (P < 0.05) in normotensive and hypertensive patients. The increase in noradrenaline concentration after tracheal intubation was greater than that after LMA insertion (P < 0.05). No patient revealed ECG evidence of myocardial ischaemia. We conclude that insertion of LMA is associated with less circulatory responses than tracheal intubation in both normotensive and hypertensive patients.
Authors:
Y Fujii; H Tanaka; H Toyooka
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  42     ISSN:  0832-610X     ISO Abbreviation:  Can J Anaesth     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-04-14     Completed Date:  1995-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  32-6     Citation Subset:  IM    
Affiliation:
Department of Anaesthesiology, Toride Kyodo General Hospital, Ibaraki, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anesthesia, Intravenous
Blood Pressure / physiology*
Cardiac Complexes, Premature / etiology
Double-Blind Method
Epinephrine / blood
Female
Heart Rate / physiology*
Humans
Hypertension / physiopathology*
Intubation, Intratracheal* / instrumentation
Laryngeal Masks*
Male
Middle Aged
Myocardial Infarction / etiology
Neuromuscular Junction / drug effects
Norepinephrine / blood
Succinylcholine / administration & dosage
Thiopental / administration & dosage
Ventricular Dysfunction / etiology
Chemical
Reg. No./Substance:
306-40-1/Succinylcholine; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 76-75-5/Thiopental

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