| Circulatory and metabolic effects of acute beta 1-blockade in severe pre-eclampsia. | |
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MedLine Citation:
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PMID: 43657 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Five mg of a beta 1-adrenoceptor antagonist (atenolol) was given i.v. to 5 women with severe pre-eclampsia in the 3rd trimester of pregnancy. There was a significant decrease of both mean systolic blood pressure, from 171 to 155 mm Hg, and mean diastolic blood pressure, from 116 to 107 mm Hg. The mean maternal heart rate decreased significantly from 90 to 74 and mean fetal heart rate significantly from 145 to 138 beats per min. There were no significant changes in the plasma levels of cyclic AMP, insulin, glucose, free fatty acids, 3-hydroxy-butyrate or glycerol. |
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Authors:
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N O Lunell; B Persson; G Aragon; B B Fredholm; H Aström |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 58 ISSN: 0001-6349 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 1979 |
Date Detail:
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Created Date: 1980-04-17 Completed Date: 1980-04-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 443-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic beta-Antagonists / adverse effects* Adult Atenolol / adverse effects*, therapeutic use Blood Glucose / analysis Blood Pressure / drug effects Cyclic AMP / blood Fatty Acids, Nonesterified / blood Female Fetal Heart / drug effects Fetus / drug effects* Glycerol / blood Heart Rate / drug effects Humans Hydroxybutyrates / blood Infant, Newborn Insulin / blood Pre-Eclampsia / drug therapy* Pregnancy Propanolamines / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Blood Glucose; 0/Fatty Acids, Nonesterified; 0/Hydroxybutyrates; 0/Propanolamines; 11061-68-0/Insulin; 29122-68-7/Atenolol; 56-81-5/Glycerol; 60-92-4/Cyclic AMP |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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