| Circulatory effects of apnoea in elite breath-hold divers. | |
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MedLine Citation:
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PMID: 19254286 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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AIM: Voluntary apnoea induces several physiological adaptations, including bradycardia, arterial hypertension and redistribution of regional blood flows. Elite breath-hold divers (BHDs) are able to maintain very long apnoea, inducing severe hypoxaemia without brain injury or black-out. It has thus been hypothesized that they develop protection mechanisms against hypoxia, as well as a decrease in overall oxygen uptake. METHODS: To test this hypothesis, the apnoea response was studied in BHDs and non-divers (NDs) during static and dynamic apnoeas (SA, DA). Heart rate, arterial oxygen saturation (SaO(2)), and popliteal artery blood flow were recorded to investigate the oxygen-conserving effect of apnoea response, and the internal carotid artery blood flow was used to examine the mechanisms of cerebral protection. RESULTS: The bradycardia and peripheral vasoconstriction were accentuated in BHDs compared with NDs (P < 0.01), in association with a smaller SaO(2) decrease (-2.7% vs. -4.9% during SA, P < 0.01 and -6% vs. -11.3% during DA, P < 0.01). Greater increase in carotid artery blood flow was also measured during apnoea in BHDs than in controls. CONCLUSION: These results confirm that elite divers present a potentiation of the well-known apnoea response in both SA and DA conditions. This response is associated with higher brain perfusion which may partly explain the high levels of world apnoea records. |
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Authors:
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Fabrice Joulia; F Lemaitre; P Fontanari; M L Mille; P Barthelemy |
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Publication Detail:
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Type: Journal Article Date: 2009-02-28 |
Journal Detail:
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Title: Acta physiologica (Oxford, England) Volume: 197 ISSN: 1748-1716 ISO Abbreviation: Acta Physiol (Oxf) Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101262545 Medline TA: Acta Physiol (Oxf) Country: England |
Other Details:
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Languages: eng Pagination: 75-82 Citation Subset: IM |
Affiliation:
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UMR MD2 P2COE, IFR Jean Roche, Faculté de Médecine secteur Nord Marseille, Marseilles, France. joulia@univ-tln.fr |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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