| Circulating serotonin in vertebrates. | |
| | |
MedLine Citation:
|
PMID: 16041566 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The role of circulating serotonin is unclear and whether or not serotonin is present in the blood of non-mammalian species is not known. This study provides the first evidence for the presence of serotonin in thrombocytes of birds and three reptilian species, the endothermic leatherback sea turtle, the green sea turtle and the partially endothermic American alligator. Thrombocytes from a fresh water turtle, American bullfrog, Yellowfin tuna, and Chinook salmon did not contain serotonin. Serotonin is a vasoactive substance that regulates skin blood flow, a major mechanism for endothermic body temperature regulation, which could explain why circulating serotonin is present in warm-blooded species. The temperature sensitivity of human blood platelets with concomitant changes in serotonin content further supports a link between circulating serotonin and thermoregulation. Phylogenetic comparison of the presence of circulating serotonin indicated an evolutionary divergence within reptilian species that might coincide with the emergence of endothermy. |
| | |
Authors:
|
E Maurer-Spurej |
Related Documents
:
|
8522566 - Phenomenon of concentrical spiral separation of microparticles in laminar vortical bloo... 4023926 - Contribution of circulating formed elements to prostanoid production in complement-medi... 9175146 - Assessment of cerebral blood flow and metabolism in vertebrobasilar insufficiency with ... 10832086 - Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood. 19054376 - Applying molecular immunohematology discoveries to standards of practice in blood banks... 11955836 - Last performance with viagra: post-mortem identification of sildenafil and its metaboli... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Cellular and molecular life sciences : CMLS Volume: 62 ISSN: 1420-682X ISO Abbreviation: Cell. Mol. Life Sci. Publication Date: 2005 Aug |
Date Detail:
|
Created Date: 2005-08-31 Completed Date: 2005-10-28 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9705402 Medline TA: Cell Mol Life Sci Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 1881-9 Citation Subset: IM |
Affiliation:
|
Department of Pathology, University of British Columbia, Vancouver, Canada. emaurer@interchange.ubc.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alligators and Crocodiles Animals Birds Blood Platelets / metabolism, ultrastructure Body Temperature Calcium / metabolism Chromatography, High Pressure Liquid Elephants Evolution Fishes Humans Microscopy, Electron, Transmission Phylogeny Rana catesbeiana Sea Lions Serotonin / blood* Species Specificity Turtles Vertebrates / blood* |
| Chemical | |
Reg. No./Substance:
|
50-67-9/Serotonin; 7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bacterial signal peptide recognizes HeLa cell mitochondrial import receptors and functions as a mito...
Next Document: Nucleotide analogues as probes for DNA polymerases.