| Circulating pro-inflammatory cytokines are elevated and peak power output correlates with 25-hydroxyvitamin D in vitamin D insufficient adults. | |
| | |
MedLine Citation:
|
PMID: 23292315 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The purpose of this study was to identify circulating cytokines, skeletal muscle strength, and peak power output in young adults with contrasting serum 25-hydroxyvitamin D (25(OH)D) concentrations. Serum 25(OH)D, inflammatory cytokines, muscle strength, and peak power output were, therefore, measured in young adults (25-42 years). Data were collected during the winter to avoid the seasonal influence on serum 25(OH)D. After serum 25(OH)D concentration measurements, subjects were separated into one of two groups: (1) vitamin D insufficient [serum 25(OH)D ≤32 ng/mL, n = 14], or (2) vitamin D sufficient [serum 25(OH)D >32 ng/mL, n = 14]. Following group allocation, serum 25(OH)D concentrations were significantly (p < 0.05) lower and pro-inflammatory cytokines [interleukin (IL)-2, IL-1β, tumor necrosis factor-α, and interferon-γ] were significantly (all p < 0.05) greater in vitamin D insufficient adults. An anti-inflammatory cytokine (i.e., IL-10; p > 0.05), peak isometric forces (p > 0.05), and peak power outputs (p > 0.05) were not significantly different between vitamin D groups. However, peak power outputs correlated with serum 25(OH)D concentrations in vitamin D insufficient (r = 0.55, p < 0.05) but not in vitamin D sufficient adults (r = -0.27, p = 0.36). Based on these data, we conclude that vitamin D insufficiency, in part, could result in pro-inflammatory stress without altering muscular strength or function in young adults. Future research investigating the causality of the correlation between low-serum 25(OH)D and peak power output in young adults is required. |
| | |
Authors:
|
Tyler Barker; Thomas B Martins; Harry R Hill; Carl R Kjeldsberg; Brian M Dixon; Erik D Schneider; Vanessa T Henriksen; Lindell K Weaver |
Related Documents
:
|
2794875 - Additional electrophoretic components of cholinesterase in plasma: a phenomenon of no i... 23426585 - Professional ski waxers' exposure to pfas and aerosol concentrations in gas phase and d... 23356505 - Effect of folic acid and zinc sulphate on endocrine parameters and seminal antioxidant ... 23313605 - Blunted salivary and plasma cortisol response in patients with panic disorder under psy... 1495285 - The determinants of elevated total plasma cholesterol levels in cardiac transplant reci... 21480145 - Acromegaly caused by ectopic growth hormone-releasing hormone production from a bronchi... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-6 |
Journal Detail:
|
Title: European journal of applied physiology Volume: - ISSN: 1439-6327 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
The Orthopedic Specialty Hospital, 5848 S. Fashion Blvd, Murray, UT, 84107, USA, tyler.barker@imail.org. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The oncolytic herpes simplex virus vector G47? effectively targets breast cancer stem cells.
Next Document: Trace Metals in Fleece Wool and Correlations with Yellowness.