Document Detail


Circulating nucleic acids and critical illness.
MedLine Citation:
PMID:  17108220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews some of the early work that has been performed to investigate the potential roles of circulating nucleic acids as prediction markers in acute illness and injury. Circulating DNA and RNA concentrations are elevated early in patients with trauma, stroke and ACS, and are generally highest in patients with a high risk of death. Circulating nucleic acids may be useful markers for the evaluation and risk-stratification of such patients.
Authors:
Timothy H Rainer; Nicole Y L Lam
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1075     ISSN:  0077-8923     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-01-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271-7     Citation Subset:  IM    
Affiliation:
Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR. thrainer@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Biological Markers
Coronary Disease / blood,  diagnosis,  epidemiology,  genetics
Critical Illness*
Humans
Nucleic Acids / blood*
Predictive Value of Tests
Risk Factors
Stroke / blood,  diagnosis,  epidemiology,  genetics
Wounds and Injuries / blood,  diagnosis,  epidemiology,  genetics
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Nucleic Acids

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