Document Detail


Circulating matrix metalloproteinase-1 and -3 in patients with an acute coronary syndrome.
MedLine Citation:
PMID:  14675588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To elucidate the diagnostic value of serum matrix metalloproteinase (MMP) levels, we measured MMP-1 and MMP-3 by a 1-step sandwich enzyme immunoassay. The transcardiac gradients of both MMPs were greater in patients with unstable angina and acute myocardial infarction than in patients with stable effort angina or control patients. Serum MMP levels appear to be a marker of plaque instability in patients with acute coronary syndrome.
Authors:
Teruo Inoue; Toru Kato; Kan Takayanagi; Toshihiko Uchida; Isao Yaguchi; Hirotoshi Kamishirado; Shigenori Morooka; Nobuo Yoshimoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  92     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-16     Completed Date:  2004-01-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1461-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine, Koshigaya, Saitama, Japan. inouet@dokkyomed.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / blood*
Angina, Unstable / blood*
Biological Markers / blood
Case-Control Studies
Coronary Angiography
Female
Humans
Immunoenzyme Techniques
Male
Matrix Metalloproteinase 1 / blood*
Matrix Metalloproteinase 3 / blood*
Middle Aged
Myocardial Infarction / blood*
Tissue Inhibitor of Metalloproteinase-1 / blood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Tissue Inhibitor of Metalloproteinase-1; EC 3.4.24.17/Matrix Metalloproteinase 3; EC 3.4.24.7/Matrix Metalloproteinase 1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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