| Circulating levels of pregnancy-associated plasma protein-A (PAPP-A) and human chorionic gonadotrophin (hCG) in intrauterine and extrauterine pregnancies. | |
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MedLine Citation:
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PMID: 6188479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnancy-associated plasma protein-A (PAPP-A) and human chorionic gonadotrophin (hCG) have been measured in the plasma of pregnant and non-pregnant women attending the outpatient clinic for suspicion of pregnancy. The plasma concentrations obtained were grouped into intrauterine or extrauterine pregnancies and compared with values obtained in non-pregnant patients with similar periods of amenorrhoea. Patients with ectopic pregnancies had slightly lower PAPP-A levels and significantly lower hCG concentrations than those in women with normal intrauterine pregnancies. Non-pregnant women had very low hCG and PAPP-A levels compared with those in pregnant patients. These data suggest that in patients with extrauterine pregnancies the poorly sustained ectopic trophoblast is unable to produce normal concentrations of hCG and probably PAPP-A and that the slightly diminished levels of PAPP-A in ectopic pregnancies might be derived from a decidual production. |
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Authors:
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P Bischof; H Reyes; W L Herrmann; P C Sizonenko |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of obstetrics and gynaecology Volume: 90 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1983 Apr |
Date Detail:
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Created Date: 1983-06-23 Completed Date: 1983-06-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 323-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chorionic Gonadotropin
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blood* Female Humans Pregnancy Pregnancy Proteins / analysis* Pregnancy, Ectopic / blood* Pregnancy-Associated Plasma Protein-A / analysis* Radioimmunoassay |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 0/Pregnancy Proteins; EC 3.4.24.-/Pregnancy-Associated Plasma Protein-A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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