| Circulating immune complexes in diabetics: the influence of sex, age, duration of disease and type of treatment. | |
| | |
MedLine Citation:
|
PMID: 6348294 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The influence of sex, age, duration of diabetes and type of antidiabetic treatment on soluble immune complexes levels was investigated in the sera of 276 randomly selected diabetics. Immune complexes were detected by the solid phase C1q binding test. The prevalence of immune complexes was significantly higher in insulin treated than in non-insulin treated diabetics. Within the insulin treated group, the prevalence in diabetics of 11-20 yr duration was significantly higher than in the remainder. No difference in immune complexes levels was found between males and females. The age of the patients did not have any correlation with the levels of immune complexes. These findings suggest that some of the immune complexes detected in randomly selected diabetics are related to insulin treatment, reflecting either differences in the type of diabetes or the effects of heterologous insulin. |
| | |
Authors:
|
U Di Mario; W J Irvine; K Guy; D Q Borsey; M Iavicoli; L Ventriglia |
Related Documents
:
|
18187074 - Carmela: assessment of cardiovascular risk in seven latin american cities. 15485414 - Albuminuria predicting outcome in diabetes: incidence of microalbuminuria in asia-pacif... 9162614 - The epidemiology of diabetes and its complications in new zealand. 1299074 - Diabetes in mexico--a serious and growing problem. 4037684 - Assessment of complications in children with insulin-dependent diabetes mellitus. 12099314 - The pathophysiology of the fetus of the diabetic mother. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of clinical & laboratory immunology Volume: 11 ISSN: 0141-2760 ISO Abbreviation: J Clin Lab Immunol Publication Date: 1983 May |
Date Detail:
|
Created Date: 1983-09-09 Completed Date: 1983-09-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7808987 Medline TA: J Clin Lab Immunol Country: ITALY |
Other Details:
|
Languages: eng Pagination: 17-20 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Age Factors Aged Antigen-Antibody Complex / analysis* Child Child, Preschool Diabetes Mellitus / drug therapy, immunology* Female Humans Infant Infant, Newborn Insulin / therapeutic use Male Middle Aged Sex Factors Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Antigen-Antibody Complex; 11061-68-0/Insulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The oligodendroglial cell: biology and immunology and relationship to multiple sclerosis.
Next Document: Neutrophil iodination micro-method as an index of neutrophil and opsonic function.