Document Detail


Circulating and exhaled vascular endothelial growth factor in asthmatic pregnancy.
MedLine Citation:
PMID:  22900522     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Context: Vascular endothelial growth factor (VEGF) plays a role in asthma and pathological pregnancies. Objective: This is the first study assessing plasma and exhaled breath condensate VEGF levels in asthmatic pregnancy. Material and methods: Thirty-one asthmatic pregnant, 29 asthmatic nonpregnant, 28 healthy pregnant and 22 healthy nonpregnant women were enrolled. Plasma was collected in all subjects, EBC in 57 volunteers for VEGF measurements. Results: Plasma VEGF decreased in both pregnant groups (p < 0.01), without any differences between the asthmatic and the respective nonasthmatic groups (p > 0.05). VEGF was undetectable in EBC. Conclusion: Concomitant asthma does not affect plasma VEGF during pregnancy.
Authors:
Andras Bikov; Aniko Bohacs; Noemi Eszes; Zsoka Weiszhar; Istvan Ivancso; Veronika Muller; Janos Rigo; Gyorgy Losonczy; Lilla Tamasi; Ildiko Horvath
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-20
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  -     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pulmonology, Semmelweis University , Budapest , Hungary.
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