Document Detail


The circle before willis: a historical account of the intracranial anastomosis.
MedLine Citation:
PMID:  19935436     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The circle of Willis is one of the most famous eponymous structures in human anatomy. There is no doubt Thomas Willis at Oxford accurately demonstrated the anastomotic arterial supply at the base of the brain. However, this eponymous name does not reveal the history of the discovery of the ramification, nor does it give credit to the anatomists and artists who have contributed to the understanding of this clinically important structure. This article first traces the story of the discovery of the circle of Willis. Willis' contribution and innovative approaches are then discussed. Finally, despite Willis' not being the first to describe the circle, we explain why he still deserves to retain the eponymous title. The earlier description of the vasculature at the base of the brain was fixated on a nonexistent structure, at least not in humans, named the rete mirabile. The more scientific study of the blood supply to the brain took place during the Renaissance period, which culminated in the work of Thomas Willis in the 17th century.
Authors:
William B Lo; Harold Ellis
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Publication Detail:
Type:  Biography; Historical Article; Journal Article; Portraits    
Journal Detail:
Title:  Neurosurgery     Volume:  66     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-22     Completed Date:  2010-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-18; discussion 17-8     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, B15 2TH, United Kingdom. williamlo@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Arteriovenous Anastomosis / anatomy & histology,  surgery
Circle of Willis / anatomy & histology*,  physiology*,  surgery
Eponyms*
Famous Persons
History, 15th Century
History, 16th Century
History, 17th Century
History, 18th Century
History, Medieval
Humans
Medical Illustration / history
Neuroanatomy / history*
Personal Name Subject
Personal Name Subject:
Thomas Willis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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