Document Detail

Circannual changes in the duration of the immobility response of rats in the forced swim test.
MedLine Citation:
PMID:  8587969     Owner:  NLM     Status:  MEDLINE    
Separate groups of male rats were tested in the forced swim test on the third Tuesday of each mo for 14 mo. A distinct pattern was observable in their immobility response such that animals were most immobile during the winter months (Dec-Mar) and least immobile during the summer months (June-Sept). Bicarbonate-carbon dioxide levels were significantly correlated with immobility times (r = 0.48), as were glucose (r = 0.34) and phosphorus (r = -0.33) levels, whereas corticosterone and testosterone levels were not significantly correlated with immobility. These results indicate that there is a circannual rhythm in the floating behavior of rats in the forced swim test.
E L Abel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology & behavior     Volume:  58     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1996-03-25     Completed Date:  1996-03-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  591-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI, USA.
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MeSH Terms
Arousal / physiology*
Bicarbonates / blood
Blood Glucose / metabolism
Carbon Dioxide / blood
Corticosterone / blood
Motor Activity / physiology*
Rats, Sprague-Dawley
Testosterone / blood
Reg. No./Substance:
0/Bicarbonates; 0/Blood Glucose; 124-38-9/Carbon Dioxide; 50-22-6/Corticosterone; 58-22-0/Testosterone

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