Document Detail


Circadian variation of endothelial function in idiopathic dilated cardiomyopathy.
MedLine Citation:
PMID:  16490441     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study measured flow-mediated dilation (FMD) of the brachial artery 3 times a day (6:30 a.m., 11:30 a.m., and 9 p.m.) in 7 normal subjects and 14 patients with idiopathic dilated cardiomyopathy (7 in New York Heart Association [NYHA] functional class I or II and 7 in NYHA functional class III or IV). FMD in normal subjects and patients in NYHA class I or II showed a circadian variation, being lowest in the morning and highest at night. Compared with them, FMD in patients in NYHA class III or IV was lower and almost constant during the day, showing loss of significant circadian variation in endothelial function in patients with congestive heart failure.
Authors:
Takeshi Maruo; Satoshi Nakatani; Hideaki Kanzaki; Hiroyuki Kakuchi; Masakazu Yamagishi; Masafumi Kitakaze; Tohru Ohe; Kunio Miyatake
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-09
Journal Detail:
Title:  The American journal of cardiology     Volume:  97     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-21     Completed Date:  2006-04-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  699-702     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Okayama, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Atrial Natriuretic Factor / blood
Biological Markers / blood
Blood Flow Velocity
Brachial Artery / physiopathology
Cardiomyopathy, Dilated / drug therapy,  physiopathology*
Case-Control Studies
Circadian Rhythm* / drug effects
Endothelium, Vascular / drug effects,  physiopathology*
Female
Forearm / blood supply
Heart Rate
Humans
Male
Middle Aged
Natriuretic Peptide, Brain / blood
Nitroglycerin / therapeutic use
Regional Blood Flow
Stroke Volume
Treatment Outcome
Vasodilation / drug effects
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Vasodilator Agents; 114471-18-0/Natriuretic Peptide, Brain; 55-63-0/Nitroglycerin; 85637-73-6/Atrial Natriuretic Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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