| Circadian topology of metabolism. | |
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MedLine Citation:
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PMID: 23151577 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Biological clocks are genetically encoded oscillators that allow organisms to anticipate changes in the light-dark environment that are tied to the rotation of Earth. Clocks enhance fitness and growth in prokaryotes, and they are expressed throughout the central nervous system and peripheral tissues of multicelled organisms in which they influence sleep, arousal, feeding and metabolism. Biological clocks capture the imagination because of their tie to geophysical time, and tools are now in hand to analyse their function in health and disease at the cellular and molecular level. |
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Authors:
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Joseph Bass |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nature Volume: 491 ISSN: 1476-4687 ISO Abbreviation: Nature Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0410462 Medline TA: Nature Country: England |
Other Details:
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Languages: eng Pagination: 348-56 Citation Subset: IM |
Affiliation:
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Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. j-bass@northwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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P01AG011412/AG/NIA NIH HHS; P60 DK020595/DK/NIDDK NIH HHS; R01DK090625/DK/NIDDK NIH HHS; R01HL097817/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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