Document Detail


Circadian rhythms and patterns of performance before and after simulated jet lag.
MedLine Citation:
PMID:  2801999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have developed a rhesus monkey model that enables us to investigate physiological rhythms and circadian effects on performance in an integrated framework. Monkeys worked for 8 h/day on a two-component task (a vigilance trial followed by a discrimination trial) for their daily food aliquot. Concurrently, we recorded activity and temperature rhythms around the clock. To test the model, we studied rhythms and performance during entrainment to a 24-h light cycle and after a 6-h phase advance. Results from this animal model displayed many of the essential characteristics seen in similar human experiments. During stable entrainment, temperature rhythms reached their maximum amplitude in late afternoon, with activity rhythms reaching their maximum amplitude several hours earlier. Performance exhibited consistent task-dependent variations over the course of daily sessions. Speed of discrimination performance was fastest at the beginning of the session, and speed of vigilance performance was fastest several hours later. After a 6-h phase advance, monkeys exhibited transient internal desynchrony with activity resynchronizing faster than temperature. Both vigilance and discrimination were impaired after the phase shift, with vigilance exhibiting larger-magnitude and longer-lasting impairments than discrimination. A second drop in performance was seen 10-14 days after the phase shift. These data replicate and extend earlier work in humans and show that this model can be used in the study of chronobiological questions that would be too expensive or too impractical to do with humans.
Authors:
W N Tapp; B H Natelson
Related Documents :
18681499 - Low-frequency fourier analysis of speech rhythm.
1244209 - Brain temperature in the unanaesthetized chicken: its circadian rhythm of responsivenes...
19380369 - Light-at-night, circadian disruption and breast cancer: assessment of existing evidence.
8843919 - Endogenous circadian rhythm of basal pupil size in rabbits.
3949419 - Ultradian rhythms in human fetal heart rate: a computerised time series analysis.
2656469 - Use of benzodiazepines to manipulate the circadian clock regulating behavioral and endo...
7582329 - Running discrete fourier transform for time--frequency analysis of biomedical signals.
19662949 - Terrestrial-passage theory: failing a test.
16665739 - Interaction between green and far-red light on the low fluence rate chloroplast orienta...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  257     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-17     Completed Date:  1989-11-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  R796-803     Citation Subset:  IM    
Affiliation:
Primate Neuro-behavioral Unit, Veterans Administration Medical Center, East Orange 07019.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acclimatization*
Animals
Body Temperature
Body Temperature Regulation
Circadian Rhythm*
Discrimination (Psychology)*
Macaca mulatta
Male
Travel
Wakefulness

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Renal calyceal and pelvic contraction rhythms.
Next Document:  Intrapreoptically microdialyzed and microinjected norepinephrine evokes different thermal responses.