Document Detail


Circadian rhythms: biological clocks work in phospho-time.
MedLine Citation:
PMID:  21549947     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The 24 hour molecular oscillator requires precisely calibrated degradation of core clock proteins, like PERIOD. New studies shed light on a sequential series of PERIOD phosphorylation events that first inhibits, then accelerates PERIOD degradation.
Authors:
Laura B Duvall; Paul H Taghert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current biology : CB     Volume:  21     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-09     Completed Date:  2011-09-08     Revised Date:  2014-09-19    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R305-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Clocks / physiology*
Circadian Rhythm / physiology*
Circadian Rhythm Signaling Peptides and Proteins / metabolism*,  physiology
Drosophila
Gene Expression Regulation / physiology*
Humans
Models, Biological
Phosphorylation
Grant Support
ID/Acronym/Agency:
R01 MH067122/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Circadian Rhythm Signaling Peptides and Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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