Document Detail

Circadian rhythm of the signal averaged electrocardiogram and its relation to heart rate variability in healthy subjects.
MedLine Citation:
PMID:  9659198     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the circadian variation in the signal averaged electrocardiogram (saECG) and heart rate variability and investigate their relations in healthy subjects. METHODS: 24 hour ECGs were obtained with a three channel recorder using bipolar X, Y, and Z leads in 20 healthy subjects. The following variables were determined hourly: heart rate, filtered QRS (f-QRS) duration, low and high frequency components of heart rate variability (LF and HF), and the LF/HF ratio. RESULTS: Heart rate, f-QRS duration, HF, and the LF/HF ratio showed significant circadian rhythms, as determined by the single cosinor method. Heart rate and the LF/HF ratio increased during daytime, and f-QRS duration and HF increased at night. f-QRS duration was negatively correlated with heart rate (r = 0.95, p < 0.001) and the LF/HF ratio (r = 0.94, p < 0.001) and positively with HF (r = 0.93, p < 0.001). CONCLUSIONS: f-QRS duration has a significant circadian rhythm in healthy subjects and is closely related to the circadian rhythm of autonomic tone.
M Nakagawa; T Iwao; S Ishida; H Yonemochi; T Fujino; T Saikawa; M Ito
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  79     ISSN:  1355-6037     ISO Abbreviation:  Heart     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-07-22     Completed Date:  1998-07-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  493-6     Citation Subset:  AIM; IM    
Department of Laboratory Medicine, Oita Medical University, Japan.
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MeSH Terms
Circadian Rhythm*
Electrocardiography, Ambulatory*
Heart Rate / physiology*
Signal Processing, Computer-Assisted*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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