| Circadian rhythm changes in blood pressure and heart rate during the first year after heart transplantation. | |
| | |
MedLine Citation:
|
PMID: 7947877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Heart transplant recipients (n = 11) were studied before discharge from the hospital and 1, 3, 6, and 12 months after transplantation to (1) examine systolic and diastolic blood pressure and heart rate circadian patterns, (2) detect the presence or absence of nocturnal declines, and (3) describe changes in the mean levels of systolic blood pressure, diastolic blood pressure, and heart rate. An ambulatory blood pressure-monitoring system was used to record blood pressure and heart rate at 1-hour intervals for up to 48 hours. Data were analyzed with descriptive and independent t-test statistics, as well as cosinor analysis for rhythmicity. The majority of the patients had significant (p < 0.05) circadian rhythms for systolic and diastolic blood pressure and heart rate throughout the study, but at times the systolic and diastolic blood pressure acrophases were found to be phase shifted to earlier or later along the time axis (e.g., peak values occurring at 3 AM rather than later in the morning or early afternoon), such that no relationships were found between circadian rhythms and nocturnal declines. More "normal" circadian rhythms were observed for heart rate than for systolic and diastolic blood pressures. The development of hypertension (systolic/diastolic blood pressures > 140/90 mm Hg) was common and by 6 months and 1 year after transplantation 8 of the 10 patients remaining in the study were hypertensive. Increases in mean heart rate of approximately 18% (ranging from 2% to 46%) were also observed during the first postoperative year. |
| | |
Authors:
|
D M Lanuza; K Grady; M Hetfleisch; M R Johnson |
Related Documents
:
|
6545937 - Acute physiological responses of squirrel monkeys exposed to hyperdynamic environments. 15722187 - Effects of a fast cable car ascent to an altitude of 2700 meters on eeg and ecg. 20729727 - Acute effects of passive smoking on blood pressure and heart rate in healthy females. 3608237 - The effects of simultaneous atropine and labetalol administration on cardiovascular par... 8933067 - Effects of sedation with detomidine hydrochloride on echocardiographic measurements of ... 12120967 - A prospective comparison of pedal ergometry with conventional treadmill testing in the ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Volume: 13 ISSN: 1053-2498 ISO Abbreviation: J. Heart Lung Transplant. Publication Date: 1994 Jul-Aug |
Date Detail:
|
Created Date: 1994-12-07 Completed Date: 1994-12-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9102703 Medline TA: J Heart Lung Transplant Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 614-23 Citation Subset: IM |
Affiliation:
|
Department of Medical-Surgical Nursing, Loyola University Medical Center, Chicago, Ill. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Pressure
/
physiology* Blood Pressure Monitoring, Ambulatory Circadian Rhythm / physiology* Female Follow-Up Studies Heart Rate / physiology* Heart Transplantation / physiology* Humans Hypertension / diagnosis*, epidemiology Immunosuppressive Agents / therapeutic use Length of Stay Longitudinal Studies Male Middle Aged Postoperative Complications / diagnosis*, epidemiology Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Exercise echocardiography in heart transplant recipients: a comparison with angiography and intracor...
Next Document: Pediatric heart transplantation: results of 2- and 5-year follow-up.