Document Detail


Circadian oscillators in eukaryotes.
MedLine Citation:
PMID:  20836046     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The biological clock, present in nearly all eukaryotes, has evolved such that organisms can adapt to our planet's rotation in order to anticipate the coming day or night as well as unfavorable seasons. As all modern high-precision chronometers, the biological clock uses oscillation as a timekeeping element. In this review, we describe briefly the discovery, historical development, and general properties of circadian oscillators. The issue of temperature compensation (TC) is discussed, and our present understanding of the underlying genetic and biochemical mechanisms in circadian oscillators are described with special emphasis on Neurospora crassa, mammals, and plants.
Authors:
Ingunn W Jolma; Ole Didrik Laerum; Cathrine Lillo; Peter Ruoff
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Wiley interdisciplinary reviews. Systems biology and medicine     Volume:  2     ISSN:  1939-005X     ISO Abbreviation:  Wiley Interdiscip Rev Syst Biol Med     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101516550     Medline TA:  Wiley Interdiscip Rev Syst Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  533-49     Citation Subset:  IM    
Affiliation:
Centre of Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway.
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MeSH Terms
Descriptor/Qualifier:
Animals
Circadian Clocks / genetics*,  physiology*
Drosophila melanogaster / genetics,  physiology
Eukaryota / genetics*,  physiology*
Feedback, Physiological
Humans
Mammals / genetics,  physiology
Models, Biological
Neurospora crassa / genetics,  physiology
Plant Physiological Phenomena
Plants / genetics
Systems Biology
Temperature

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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