Document Detail

Circadian intraocular pressure rhythms in athletic horses under different lighting regime.
MedLine Citation:
PMID:  19212846     Owner:  NLM     Status:  MEDLINE    
The present study was undertaken to investigate the existence of intraocular pressure (IOP) rhythms in athletic thoroughbred horses maintained under a 24 h cycle of light and darkness (LD) or under constant light (LL) or constant dark (DD) conditions. We identified an IOP circadian rhythm that is entrained to the 24 h LD cycle. IOP was low during the dark phase and high during the light phase, with a peak at the end of the light phase (ZT10). The circadian rhythm of IOP persisted in DD (with a peak at CT9.5), demonstrating an endogenous component in IOP rhythm. As previously shown in other mammalian species, horse IOP circadian rhythmicity was abolished in LL. Because tonometry is performed in horses for the diagnosis of ophthalmologic diseases, such as glaucoma or anterior uveitis, the daily variation in IOP must be taken into account in clinical practice to properly time tests and to interpret clinical findings.
Cristiano Bertolucci; Elisabetta Giudice; Francesco Fazio; Giuseppe Piccione
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chronobiology international     Volume:  26     ISSN:  1525-6073     ISO Abbreviation:  Chronobiol. Int.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-12     Completed Date:  2009-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501362     Medline TA:  Chronobiol Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  348-58     Citation Subset:  IM    
Dipartimento di Biologia ed Evoluzione, Universita di Ferrara, Ferrara, Italy.
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MeSH Terms
Biological Clocks / physiology
Circadian Rhythm / physiology*
Intraocular Pressure / physiology*
Tonometry, Ocular

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