| Circadian activity rhythms in rats with midbrain raphe lesions. | |
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MedLine Citation:
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PMID: 3779378 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dorsal and median mesencephalic raphe nuclei provide a robust projection to the hypothalamic suprachiasmatic nucleus, the site of a putative neuronal circadian pacemaker. Although it has been suggested that the raphe may play a role in the circadian timing system, this role has not yet been specified. In the present report, we examined the circadian activity patterns of rats with large mid-brain lesions aimed at the median and dorsal raphe nuclei under conditions of light-dark entrainment, and while free-running in constant light and constant darkness. The results indicate that midbrain raphe lesions may interfere with the expression of free-running circadian activity rhythms. |
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Authors:
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J D Levine; A M Rosenwasser; J A Yanovski; N T Adler |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Brain research Volume: 384 ISSN: 0006-8993 ISO Abbreviation: Brain Res. Publication Date: 1986 Oct |
Date Detail:
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Created Date: 1987-01-05 Completed Date: 1987-01-05 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0045503 Medline TA: Brain Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 240-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain Mapping Circadian Rhythm* Female Mesencephalon / physiology* Motor Activity / physiology* Raphe Nuclei / physiology* Rats Rats, Inbred Strains Serotonin / physiology Suprachiasmatic Nucleus / physiology |
| Grant Support | |
ID/Acronym/Agency:
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5-T32-GM07170/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-67-9/Serotonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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