Document Detail

Cinecoronary arteriography in young men.
MedLine Citation:
PMID:  11993306     Owner:  NLM     Status:  MEDLINE    
Of a group of 723 men less than 40 years old who underwent cinecoronary arteriography primarily for evaluation of chest pain, 357 (49%) were found to have at least 50% narrowing of one or more coronary arteries. The youngest person was 17 years old. The distribution of lesions in the young men was similar to that found earlier in a study of persons not selected by age. The anterior descending coronary artery was most frequently affected; the right coronary artery was most often totally occluded. No total occlusions of the left main coronary artery were seen. Electrocardiographic evidence of myocardial infarction, found in 109 patients, was less common with disease of the circumflex or right coronary arteries than with disease of the anterior descending coronary artery. This observation was confirmed by examination of left ventriculograms for areas of decreased contractility. Six patients had no significant arterial narrowing. The extent of arterial involvement seemed to be related to the duration of symptoms in patients who had angina pectoris or myocardial infarctions. Clinical diagnoses correlated well with the angiographic findings, particularly in those men considered to be normal and those with typical angina pectoris. Addition of atypical features or prolonged pain decreased the degree of correlation. Only 20% of those with cholesterol levels less than 200 mg/100 ml had significant lesions, whereas 81% with levels more than 275 mg/100 ml had such findings.
C C Welch; W L Proudfit; F M Sones; E K Shirey; W C Sheldon; M Razavi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  42     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  1970 Oct 
Date Detail:
Created Date:  2002-05-07     Completed Date:  2002-05-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  647-52     Citation Subset:  AIM; IM    
Department of Clinical Cardiology, Department of Cardiovascular Disease and Cardiac Laboratory, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
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MeSH Terms
Angina Pectoris / diagnosis
Cholesterol / blood
Coronary Angiography
Coronary Artery Disease / blood,  diagnosis,  radiography*
Myocardial Infarction / diagnosis
Reg. No./Substance:

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