| Cimetidine treatment of recurrent ulcer. | |
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MedLine Citation:
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PMID: 531516 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-one consecutive patients with endoscopically proven recurrent ulcer were treated continuously with cimetidine, 1 g daily for 8 weeks. After 4 weeks' treatment 18 (86%) of the patients were free of symptoms, and the ulcers had healed in 17 (81%). At the 8th-week examination symptoms had disappeared, and ulcers were healed in 19 patients (91%). Within 6 weeks after withdrawal of cimetidine six patients (28%) presented recurrence of ulcers and symptoms. This study demonstrates that recurrent ulcer patients respond to cimetidine with regard to healing of ulcers and disappearance of symptoms, as do unoperated duodenal ulcer patients. Because operation for recurrent ulcer carries an increased mortality, we suggest that cimetidine should be attempted in the treatment. |
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Authors:
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J G Stage; F W Henriksen; H Kehlet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of gastroenterology Volume: 14 ISSN: 0036-5521 ISO Abbreviation: Scand. J. Gastroenterol. Publication Date: 1979 |
Date Detail:
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Created Date: 1980-04-25 Completed Date: 1980-04-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0060105 Medline TA: Scand J Gastroenterol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 977-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cimetidine / therapeutic use* Drug Evaluation Duodenal Ulcer / drug therapy*, surgery Female Gastric Juice / secretion Gastrins / blood Guanidines / therapeutic use* Humans Male Middle Aged Recurrence Stomach Ulcer / drug therapy*, surgery |
| Chemical | |
Reg. No./Substance:
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0/Gastrins; 0/Guanidines; 51481-61-9/Cimetidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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