| Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. | |
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MedLine Citation:
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PMID: 6908433 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied. Although both doses of Cimetidine reduced the acid secretion significantly, no reduction in the steatorrhea and creatorrhea or increase in weight were found, although less pancreatin seemed to be inactivated while on cimetidine. It is concluded that pancreatic extract supplementation alone is not sufficient to normalise the digestion in cystic fibrosis. |
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Authors:
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F de Biéville; H J Neijens; J Fernandes; M van Caillie; K F Kerrebijn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta paediatrica Scandinavica Volume: 70 ISSN: 0001-656X ISO Abbreviation: Acta Paediatr Scand Publication Date: 1981 Jan |
Date Detail:
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Created Date: 1981-05-26 Completed Date: 1981-05-26 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0000211 Medline TA: Acta Paediatr Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 33-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adolescent Body Weight Celiac Disease / drug therapy Child Cimetidine / therapeutic use* Cystic Fibrosis / drug therapy* Drug Therapy, Combination Feces / analysis Gastric Acid / drug effects Guanidines / therapeutic use* Humans Intestinal Absorption / drug effects Lipids / analysis Malabsorption Syndromes / drug therapy*, etiology Nitrogen / analysis Pancreatin / therapeutic use* Secretory Rate / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Guanidines; 0/Lipids; 51481-61-9/Cimetidine; 7727-37-9/Nitrogen; 8049-47-6/Pancreatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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