Document Detail


Cilostazol in patients with ischemic stroke.
MedLine Citation:
PMID:  21548722     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Introduction: Several antiplatelets have been used in the prevention of secondary ischemic strokes with limited success and some carried a high risk of bleeding. Cilostazol is a relatively new antiplatelet that has been thoroughly investigated in Japan with promising outcome in secondary stroke prevention. Areas covered: In this paper, the findings of major clinical trials and the efficacy of cilostazol in preventing ischemic stroke in comparison with other more commonly used antiplatelet medications like aspirin and clopidogrel are summarized. Pharmacology and mechanism of action are also discussed. Expert opinion: Cilostazol is a safe and effective medication. It has an antiplatelet, antithrombotic and vascular endothelial proliferation inhibitory effect that makes it an excellent, promising drug for the prevention of secondary ischemic stroke and poststent thrombosis.
Authors:
Zaid A Al-Qudah; Ameer E Hassan; Adnan I Qureshi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-6
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  -     ISSN:  1744-7666     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
University of Minnesota, Zeenat Qureshi Stroke Research Center, Department of Neurology, 82 - 100 Phillips Wangensteen Building, 420 Delaware Street SE, Minneapolis, Minnesota 55455, USA qureshai@gmail.com.
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