Document Detail

Ciliary ganglioplegic migraine: Migraine-related prolonged mydriasis.
MedLine Citation:
PMID:  20847085     Owner:  NLM     Status:  In-Data-Review    
Background: Transient, unilateral mydriasis has been reported in migraine patients, and this has been regarded as a possible co-morbidity between migraine and Adie's tonic pupil. Mydriasis that outlasts the duration of migraine attacks is rare. Methods: Through an eight-year period we have studied all patients referred to our neurological clinic because of migraine attack with mydriasis. All the patients underwent thorough neurologic and ophthalmologic examinations including MRI of the brain and testing of the pupil response to ocular instillation of dilute pilocarpine (0.125%). Results: Seven women and two men, with a mean age of 33.8 ± 12.3 years (range: 19-52) were included. The patients presented during one hemicranial migraine attack with an ipsilateral mydriasis that persisted for a mean of three months, while migraine headaches remained with their typical episodic course. In all the patients a cholinergic supersensitivity in the symptomatic pupil was demonstrated, thus pointing to a dysfunction of the ipsilateral ganglionic parasympathetic fibers. Conclusions: Synchronous co-localization of the features suggests a pathogenic link between the pupil dysfunction and migraine, rather than a simultaneous coexistence of two independent disorders. Likely explanations include a latent Adie's pupil that could have been triggered during a particular migraine attack; a ciliar ganglionic lesion/dysfunction produced by the migrainous process; an ophthalmoplegic migraine with selective parasympathycoparesis; or an episodic ciliar ganglionitis with migrainous features. Ciliary ganglioplegic migraine is proposed as a nominal term pointing to the possible anatomic source of the migrainous-related pupil dysfunction; the pathogenesis remains unknown.
Fj Barriga; C López de Silanes; P Gili; Ja Pareja
Related Documents :
8342755 - The sprotte needle and post dural puncture headache following caesarean section.
10090425 - Grepafloxacin: a review of its safety profile based on clinical trials and postmarketin...
12390645 - Efficacy of topiramate in migraine prophylaxis: a retrospective chart analysis.
2522805 - Outpatient myelography: an acceptable and cost-effective technique.
1759765 - Erica predicts response to tamoxifen in elderly women with breast cancer.
19781105 - Il-6 predicts organ dysfunction and mortality in patients with multiple injuries.
Publication Detail:
Type:  Journal Article     Date:  2010-09-16
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  31     ISSN:  1468-2982     ISO Abbreviation:  Cephalalgia     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  England    
Other Details:
Languages:  eng     Pagination:  291-5     Citation Subset:  IM    
University Hospital Fundación Hospital Alcorcón, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Characterization of consistent triggers of migraine with aura.
Next Document:  Treatment of concurrent metastatic renal cell carcinoma and chronic myelogenous leukemia - easier sa...