Document Detail


Cigarette smoking and acute leukemia.
MedLine Citation:
PMID:  15359988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent cohort and case-control studies have suggested that cigarette smoking may be involved in the etiology of leukemia. Rising trends have been observed for all leukemias when the amount of cigarettes smoked increased. However, the magnitude of the trend was strongest for myeloid leukemia. Although no detailed biological mechanism has been proposed, a causal link is made plausible by evidence of systemic effects of cigarette smoke and the presence in cigarette smoke of chemicals (benzene) and radioactive substances that have been associated with leukemia risk. Cigarette smoking has a deleterious effect on survival in leukemia by shortening complete remission duration and subsequent survival. The data reported in this review are derived from the medical literature and from the experience of the authors.
Authors:
Xavier Thomas; Youcef Chelghoum
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Leukemia & lymphoma     Volume:  45     ISSN:  1042-8194     ISO Abbreviation:  Leuk. Lymphoma     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-09-13     Completed Date:  2004-10-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9007422     Medline TA:  Leuk Lymphoma     Country:  England    
Other Details:
Languages:  eng     Pagination:  1103-9     Citation Subset:  IM    
Affiliation:
Leukemia unit, Hematology Department, Edouard Herriot Hospital, Lyon, France. xavier.thomas@chu-lyon.fr
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Humans
Leukemia / etiology*,  pathology
Risk Factors
Smoking / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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