Document Detail


Cidea promotes hepatic steatosis by sensing dietary fatty acids.
MedLine Citation:
PMID:  22278400     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: Cidea plays critical roles in promoting hepatic lipid accumulation and in the development of hepatic steatosis by acting as a sensor that responds to diets that contain FAs.
Authors:
Linkang Zhou; Li Xu; Jing Ye; De Li; Wenshan Wang; Xuanhe Li; Lizhen Wu; Hui Wang; Feifei Guan; Peng Li
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-06-01
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  56     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-04     Completed Date:  2012-10-17     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-107     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
Affiliation:
Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Apoptosis Regulatory Proteins / metabolism*
Biopsy, Needle
Disease Models, Animal
Fatty Acids / metabolism*
Fatty Liver / genetics,  metabolism*
Gene Expression
Hepatocytes / metabolism,  pathology
Humans
Immunohistochemistry
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Obese
Random Allocation
Reference Values
Sensitivity and Specificity
Sterol Regulatory Element Binding Protein 1 / metabolism*
Chemical
Reg. No./Substance:
0/Apoptosis Regulatory Proteins; 0/Cidea protein, mouse; 0/Fatty Acids; 0/Sterol Regulatory Element Binding Protein 1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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