| Ciclosporin in minimal-change glomerulopathy and in focal segmental glomerular sclerosis. | |
| | |
MedLine Citation:
|
PMID: 2256469 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Results of the available literature and preliminary data of an ongoing multicenter, prospective, randomized Italian trial indicate that ciclosporin (CS), at low doses, may maintain remission of the nephrotic syndrome in most steroid-sensitive patients. In steroid-resistant patients CS may cause either complete or partial remission in about 40% of patients with idiopathic nephrotic syndrome. With doses not exceeding 5 mg/kg/day and careful monitoring of renal and liver function, blood pressure and blood levels, severe side effects can be prevented. Although an extensive use of CS in nephrotic syndrome is still premature, cautious trials may be attempted in patients with steroid toxicity and/or devastating nephrotic syndrome. |
| | |
Authors:
|
C Ponticelli; E Rivolta |
Related Documents
:
|
90759 - Does the nephrotic syndrome increase the risk of cardiovascular disease? 11320279 - Nephrotic syndrome and mesenteric infarction secondary to metastatic mesothelioma. 18583759 - Arterial thrombosis in nephrotic syndrome due to minimal change glomerulonephritis. 7573199 - Nephrotic syndrome, malignant thymoma, and myasthenia gravis. case report and review of... 9811389 - Membranous glomerulonephritis and nephrosis post factor ix infusions in hemophilia b. 7696099 - Applying decision analysis to management of adolescent idiopathic nephrotic syndrome. 2951499 - Dopaminergic neurotransmitter systems in alzheimer's disease and in down's syndrome at ... 18346989 - Serum cytokine and chemokine profiles in neonates with meconium aspiration syndrome. 22349879 - Entheseal ultrasound abnormalities in patients with sapho syndrome. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Review |
Journal Detail:
|
Title: American journal of nephrology Volume: 10 Suppl 1 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 1990 |
Date Detail:
|
Created Date: 1991-01-24 Completed Date: 1991-01-24 Revised Date: 2007-02-14 |
Medline Journal Info:
|
Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 105-9 Citation Subset: IM |
Affiliation:
|
Divisione di Nefrologia e Dialisi, Ospedale Maggiore, Milano, Italia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Child Cyclophosphamide / therapeutic use Cyclosporins / therapeutic use* Glomerulosclerosis, Focal Segmental / drug therapy* Humans Nephrosis, Lipoid / drug therapy* Nephrotic Syndrome / drug therapy* Prospective Studies |
| Chemical | |
Reg. No./Substance:
|
0/Cyclosporins; 50-18-0/Cyclophosphamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relation between lipids and atherosclerosis: epidemiologic evidence and clinical implications.
Next Document: Lipid-lowering agents in proteinuric diseases.