| Ciclopirox (Loprox) gel for superficial fungal infections. | |
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MedLine Citation:
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PMID: 15334276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ciclopirox (Loprox) is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Its main mode of action is thought to be its high affinity for trivalent cations, which inhibit essential co-factors in enzymes. Clinical trials have shown that ciclopirox gel is a successful treatment for seborrheic dermatitis of the scalp as well as for tinea pedis. Adverse effects are generally mild and include a skin-burning sensation, contact dermatitis, and pruritus. Ciclopirox is indicated in the US for the treatment of tinea pedis, tinea corporis, pityriasis versicolor, seborrheic dermatitis, and cutaneous candidiasis. |
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Authors:
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A K Gupta; R Bluhm |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Skin therapy letter Volume: 9 ISSN: 1201-5989 ISO Abbreviation: Skin Therapy Lett. Publication Date: 2004 Aug-Sep |
Date Detail:
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Created Date: 2004-08-30 Completed Date: 2004-09-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9891441 Medline TA: Skin Therapy Lett Country: Canada |
Other Details:
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Languages: eng Pagination: 4-5, 9 Citation Subset: IM |
Affiliation:
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Division of Dermatology, Department of Medicine, Sunnybrook and Womens College Health Sciences Centre (Sunnybrook site), University of Toronto, Toronto, ON, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Antifungal Agents / therapeutic use* Canada Dermatomycoses / diagnosis*, drug therapy* Dose-Response Relationship, Drug Drug Administration Schedule Female Gels Humans Male Prognosis Pyridones / therapeutic use* Randomized Controlled Trials as Topic Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 0/Gels; 0/Pyridones; 29342-05-0/ciclopirox |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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