Document Detail


Churg-Strauss syndrome associated with the leukotriene antagonist montelukast.
MedLine Citation:
PMID:  15060812     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Churg-Strauss syndrome (CSS) is a disseminated small vessel vasculitis characterized by late-onset asthma, upper airways disease, eosinophilia and late neurological manifestations such as peripheral neuropathy. Recently, several cases of CSS have been reported in patients treated with leukotriene antagonists after weaning corticosteroids. We describe a case of CSS developed while the patient was receiving montelukast for asthma treatment, after corticosteroids withdrawal. A causal relationship between montelukast therapy and CSS is hypothesized.
Authors:
C Boccagni; F Tesser; D Mittino; E Terazzi; P Naldi; S Colombi; E Zoppis; F Monaco
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology     Volume:  25     ISSN:  1590-1874     ISO Abbreviation:  Neurol. Sci.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-02     Completed Date:  2004-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100959175     Medline TA:  Neurol Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  21-2     Citation Subset:  IM    
Affiliation:
Department of Neurology, A. Avogadro University, Corso Mazzini 18, I-28100 Novara, Italy. cboccagni@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Acetates / adverse effects*
Aged
Asthma / drug therapy
Churg-Strauss Syndrome / chemically induced*,  physiopathology
Electrophysiology
Female
Humans
Leukotriene Antagonists / adverse effects*
Pain / chemically induced
Peripheral Nervous System Diseases / chemically induced
Quinolines / adverse effects*
Chemical
Reg. No./Substance:
0/Acetates; 0/Leukotriene Antagonists; 0/Quinolines; 158966-92-8/montelukast

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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