Document Detail

Chuchuhuasha - a drug used in folk medicine in the Amazonian and Andean areas. A chemical study of Maytenus laevis.
MedLine Citation:
PMID:  7033668     Owner:  NLM     Status:  MEDLINE    
In the high Amazonian basin a plant named chuchuasha, (or chuchuaso) is used in traditional medicine for several purposes in the form of an alcoholic extract. This plant, a Maytenus species, most probably Maytenus laevis, grows in the subandean region of the Amazonian basin (Peru, Ecuador, Colombia). Antitumor and anti-inflammatory properties were recently attributed to the extracts of the root bark of the plant. The composition of the extract of M. laevis from the Putumayo area of Colombia was studied in order to establish the active principle responsible for these activities. The presence of phenoldienones (tingenone, 22-hydroxytingenone), a catechin (4'-methyl-(-)-epigallocatechin) and proanthocyanidins (Ouratea-proanthocyanidins A and B) was established. The biological activities of these compounds confirm the properties of the extracts of the plant claimed by traditional medicine.
J G Gonzalez; G delle Monache; F delle Monache; G B Marini-Bettolò
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of ethnopharmacology     Volume:  5     ISSN:  0378-8741     ISO Abbreviation:  J Ethnopharmacol     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-03-22     Completed Date:  1982-03-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7903310     Medline TA:  J Ethnopharmacol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  73-7     Citation Subset:  IM    
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MeSH Terms
Antineoplastic Agents, Phytogenic / analysis*,  pharmacology
Chemical Phenomena
Plant Extracts / analysis*,  pharmacology
South America
Reg. No./Substance:
0/Antineoplastic Agents, Phytogenic; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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