Document Detail

Chronobiological rhythms in onset of massive pulmonary embolism in Iranian population.
MedLine Citation:
PMID:  19950729     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To investigate whether there is any chronobiological rhythms in onset of massive pulmonary embolism in Iranian population and to study any time variation in occurrence of this disease in patients' subgroups.
METHODS: This study was conducted in an emergency department of a referral teaching hospital from March 2003 to March 2007. All medical records of patients with definite diagnosis of massive pulmonary embolism were reviewed for chronobiological rhythms in hourly, daily, monthly and season periods.
RESULTS: One hundred and twenty patients (49 women and 71 men) included in the study. The mean age of patients was 63.63 +/- 17.21 years. Massive pulmonary embolism showed a statistical increase in onset in the morning period (p = 0.004) with peak of occurrence between 9:00 to 10:00, in the first three day of the week (p < 0.001), and during winter (p = 0.003). In addition, hourly and weekly rhythms in onset of massive pulmonary embolism in diabetic patients is different from nondiabetic patients and occur most frequent in evening hours and in the end of week.
CONCLUSION: Our findings revealed that massive pulmonary embolism has a peak of onset during morning hours and in the winter. We also found that massive pulmonary embolism also has a weekly rhythm. Circadian and weekly rhythms of massive pulmonary embolism were different in diabetic patients and this is a novel finding of this study.
Hadi Hakim; Jahanbakhsh Samadikhah; Azin Alizadehasl; Rasoul Azarfarin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Middle East journal of anaesthesiology     Volume:  20     ISSN:  0544-0440     ISO Abbreviation:  Middle East J Anaesthesiol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-12-02     Completed Date:  2010-01-05     Revised Date:  2014-10-10    
Medline Journal Info:
Nlm Unique ID:  8604187     Medline TA:  Middle East J Anaesthesiol     Country:  Lebanon    
Other Details:
Languages:  eng     Pagination:  369-75     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Circadian Rhythm*
Cross-Sectional Studies
Middle Aged
Pulmonary Embolism / etiology*,  physiopathology
Retrospective Studies
Risk Factors

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