Document Detail

Chronobiological aspects of bronchial tone.
MedLine Citation:
PMID:  7117039     Owner:  NLM     Status:  MEDLINE    
The aim of the investigation was to demonstrate the existence of cyclic variations of bronchial tone, correlated with the increase of vagal tone during nocturnal hours and with the increase of adrenergic tone in the late morning and afternoon. Twenty-five healthy subjects were tested, utilizing forced expiration curve (V/V loop), Raw and SGaw. We did not detect a statistically significant rhythm for FVC, FEV1, PEF, because they are effort-dependent parameters. On the contrary, we demonstrated significant fluctuations for V max50, FEF25.75 (acrophase in the later morning and early afternoon), for Raw (acrophase in late evening) and for SGaw (Acrophase in antiphase with Raw); these parameters are effort-independent as well as direct and sensitive indexes of the tone of peripheral and central airways.
G Ciappi; F De Benedetto; F D'Ilario; R Fuciarelli; A Luciano; M Sborgia; M Cervone; S Sensi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chronobiologia     Volume:  9     ISSN:  0390-0037     ISO Abbreviation:  Chronobiologia     Publication Date:    1982 Apr-Jun
Date Detail:
Created Date:  1982-12-02     Completed Date:  1982-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0434557     Medline TA:  Chronobiologia     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  163-72     Citation Subset:  IM    
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MeSH Terms
Bronchi / physiology*
Circadian Rhythm*
Models, Biological
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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