Document Detail

Chronobiologic evaluation of drug efficacy in hypertension.
MedLine Citation:
PMID:  1799932     Owner:  NLM     Status:  MEDLINE    
Time-associated variations of blood pressure became accessible due to the modern development of pressure monitoring technology. The data collection and analysis should be standardized and formulated. Time-associated changes of pressure were evaluated not only by nonparametric and conventional but also by parametric and rhythmometric estimation. The reference data (chronodesms) are essential to define the deviant magnitude of pressure. This chronobiologic approach became feasible to quantitate the efficacy of antihypertensive agents in hypertensives.
K Tamura
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Chronobiology international     Volume:  8     ISSN:  0742-0528     ISO Abbreviation:  Chronobiol. Int.     Publication Date:  1991  
Date Detail:
Created Date:  1992-04-22     Completed Date:  1992-04-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8501362     Medline TA:  Chronobiol Int     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  511-25     Citation Subset:  IM    
Department of Medicine and Cardiology, Yamanashi Medical College, Japan.
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Blood Pressure / drug effects,  physiology
Blood Pressure Monitors
Circadian Rhythm / physiology*
Hypertension / drug therapy*,  physiopathology
Middle Aged
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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