| Chronic villitis, chronic chorioamnionitis, and maternal floor infarction. | |
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MedLine Citation:
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PMID: 8210775 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic inflammatory infiltrates in the human placenta are much less common than acute inflammation. Most often, chronic inflammation is found in the villi (villitis), but rarely it may involve the fetal membranes. Villitis is associated with many well-documented maternal infections. Reviewed herein are features of the villous inflammatory infiltrate and associated villous changes that may suggest a specific bacterial or protozoal etiology. However, the majority of villitides are of unknown etiology. These may be the result of an unrecognized pathogen or, alternatively, may reflect an abnormal immune reaction. Chronic chorioamnionitis is commonly associated with villitis and has accompanied some well-documented viral, bacterial, and protozoal infections, but a specific infectious etiology is not identified in many cases. Maternal floor infarction is not a true infarct; it is characterized by the deposition of fibrin in the decidua basalis and intervillous space where enveloped villi become avascular and sclerotic. Maternal floor infarction is associated with intrauterine growth retardation and fetal demise. It frequently recurs in successive pregnancies. |
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Authors:
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D J Gersell |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in diagnostic pathology Volume: 10 ISSN: 0740-2570 ISO Abbreviation: Semin Diagn Pathol Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-11-04 Completed Date: 1993-11-04 Revised Date: 2007-05-16 |
Medline Journal Info:
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Nlm Unique ID: 8502262 Medline TA: Semin Diagn Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 251-66 Citation Subset: IM |
Affiliation:
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Washington University School of Medicine, St Louis, MO 63110. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chorioamnionitis
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pathology Chorionic Villi / pathology* Chronic Disease Female Humans Infarction / pathology* Listeria Infections / pathology Placenta Diseases / pathology* Pregnancy Pregnancy Complications, Parasitic / pathology Syphilis, Congenital / pathology Toxoplasmosis / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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