| Chronic ulcerative stomatitis: a distinct clinical entity? | |
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MedLine Citation:
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PMID: 21874892 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Chronic ulcerative stomatitis (CUS) is a mucocutaneous disorder which is characterised by persistent oral mucosal ulceration. The clinical appearance is often reminiscent of oral lichen planus (OLP) leading to erroneous diagnoses. The immune mediated inhibition of the CUS protein (CUSP) is implicated in the pathogenesis of CUS. CUSP acts as an anti-apoptotic protein and when its action is prevented it may result in significant epithelial injury. The objective or this article is to present the first documented case of CUS in South Africa, with relevant reference to current international literature. CUS should be considered in patients previously diagnosed with OLP but who are unresponsive to glucocorticosteroid therapy. The condition can be successfully managed using hydroxychloroquine. |
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Authors:
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J Fourie; W F P van Heerden; S C McEachen; A van Zyl |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging Volume: 66 ISSN: 1029-4864 ISO Abbreviation: SADJ Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-08-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9812497 Medline TA: SADJ Country: South Africa |
Other Details:
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Languages: eng Pagination: 119-21 Citation Subset: D |
Affiliation:
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University of Pretoria, School of Dentistry, Department of Periodontics and Oral Medicine, Pretoria. jeanine.fourie@up.ac.za |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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