Document Detail

Chronic total occlusion treatment in post-CABG patients: saphenous vein graft versus native vessel recanalization-long-term follow-up in the drug-eluting stent era.
MedLine Citation:
PMID:  17584913     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the postprocedural and long-term clinical outcomes of two groups of patients, all presenting with chronic saphenous vein graft (SVG) occlusion, who underwent either SVG or native vessel reopening. BACKGROUND: Chronic total occlusions (CTO) treatment in patients who underwent previous surgical revascularization is a dilemma and the choice of performing native vessel or SVG recanalization is not always easy. METHODS: Between July 2002 and October 2004, a total of 260 patients were successfully treated for a CTO. Of them, we selected all patients (n = 24) who had previous bypass surgery with graft occlusion. Of this final group, 13 patients underwent a percutaneous graft recanalization while 11 underwent native vessel reopening. RESULTS: Primary end points were in-hospital and 3-year rates of death, myocardial infarction, target lesion revascularization, and target vessel revascularization. No events occurred in either group during the in-hospital period. Cumulative 3-year event-free survival in the native vessel and SVG group was 81.8% and 83.9% respectively (P = NS). One death and one TVR occurred in each group. CONCLUSION: In selected cases, SVG reopening instead of the native vessel is feasible. In such a high-risk population, drug-eluting stent implantation in both SVG and native CTO lesions is associated with good long-term outcomes.
Emanuele Meliga; Héctor M García-García; Neville Kukreja; Joost Daemen; Shuzou Tanimoto; Steve Ramcharitar; Carlos A G van Mieghem; Georgios Sianos; Martin van der Ent; Willem J van der Giessen; Pim de Feyter; Ron van Domburg; Patrick W Serruys
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  70     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-28     Completed Date:  2007-08-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley-Liss, Inc.
Interventional Cardiology Department, Thoraxcenter, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects,  instrumentation*
Cardiovascular Agents / administration & dosage*
Chronic Disease
Coronary Artery Bypass*
Coronary Disease / drug therapy,  mortality,  therapy*
Feasibility Studies
Follow-Up Studies
Graft Occlusion, Vascular / drug therapy,  mortality,  therapy*
Middle Aged
Myocardial Infarction / etiology
Prosthesis Design
Retrospective Studies
Saphenous Vein / transplantation*
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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